Potential Vaccine Target for Increasingly Concerning Bacterial Strain

Scientists have discovered a key bacterial target for the development of a vaccine.

Vaccine for Acinetobacter baumannii (Bacterial Pathogen)

“Capsular polysaccharides [or carbohydrates] that cover A. baumannii are a major virulence factor that play an important role in pathogenesis, are used to assign serotypes and provide the basis for vaccine development,” the authors wrote.

The team created and screened synthetic carbohydrates resembling the capsular polysaccharides of A. baumannii and identified a likely candidate.

The work will now advance to A. baumannii challenge studies in a mouse model.

Source: Eurekalert

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