Toll Like Receptor 8 drugs in development by Therapy Areas, Indications, Stages, MoA, RoA, Molecule Type, and Key Players, 2023
The report also covers products from therapy areas such as Oncology, Immunology, and Infectious Disease which include the indications Solid Tumor, Melanoma, Systemic Lupus Erythematosus, Subacute Cutaneous Lupus Erythematosus (SCLE), Hepatitis B, and Human Immunodeficiency Virus (HIV) Infections (AIDS). It also reviews key players involved in Toll Like Receptor 8 targeted therapeutics development with respective active and dormant or discontinued products.
The Toll Like Receptor 8 pipeline targets constitutes close to 40 molecules. Out of which, approximately 39 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 1, 14, 12, 3, 16, and 3 respectively. Similarly, the universities portfolio in Discovery comprises 1 molecule.
Toll Like Receptor 8 overview
Toll-like receptor 8 is a protein encoded by the TLR8 gene. It control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
For a complete picture of Toll Like Receptor 8’s drug pipeline, buy the report here.
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