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Link Between Long COVID and Altered Heart Rate Variability

Extended Covid can cause notable alterations in both resting heart rate variability (HRV) and HRV during deep breathing.

What is Dysautonomia?

Dysautonomia, characterized by dysregulation of HRV, may explain the persistent //symptoms observed in Long Covid patients,” said the researchers from University of Santa Cruz do Sul, in the paper published in the journal Scientific Reports. “There is currently a lack of evidence demonstrating how long these autonomic symptoms persist post infection.”

For the study, the researchers included 21 patients with long Covid and 20 controls. Long Covid patients showed reduced HRV at rest and during deep breathing, but mean heart rate was significantly higher in the long Covid group than in controls. The team observed these differences during a series of tests that measured heart rate during supine positioning and breathing exercises.

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“Patients with Long Covid may present with dysautonomia characterized by an imbalance of HRV, and highlights that this dysautonomia could explain the persistent symptoms observed in patients with Long Covid,” they said. The researchers said their findings should guide treatments for long Covid fatigue and dysautonomia, CIDRAP reported.

“Our findings provide a rationale for improving fatigability with interventions aimed at improving cardiac and respiratory system autonomic control, through pharmacological and non-pharmacological measures aimed at reducing the cardiovascular risk in these patients,” the team said. “For example, cardiorespiratory rehabilitation can reduce muscle fatigue and improve cardiac autonomic function in other chronic conditions and has been the focus of numerous studies in patients with Long Covid.”

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