From Mechanisms to Dosage and Timing

family, has gained attention for its potential benefits in managing PCOS. Known for improving insulin resistance and fertility in select cases, inositol plays a vital role in regulating glucose metabolism. This supplement is particularly valuable for women with PCOS seeking to enhance their insulin sensitivity.

Dosage: 2-4 grams per day.

Mechanism: Inositol, a B vitamin, has been found to improve insulin resistance and fertility in some cases of PCOS. It plays a crucial role in insulin signal transduction, promoting better glucose metabolism.


Best Time to Take: Dividing the dosage throughout the day, with meals, can enhance absorption.


Chromium, an essential trace element, is recognized for its role in stabilizing insulin resistance and improving body mass index. With its ability to enhance the action of insulin in the body, chromium supplements offer a promising avenue for addressing metabolic imbalances commonly associated with pcos
Dosage: 200-1,000 mcg per day.

Mechanism: Chromium supplements may improve body mass index and stabilize insulin resistance by enhancing the action of insulin in the body.

Best Time to Take: It is generally recommended to take chromium with meals to optimize absorption.


Beyond its culinary appeal, cinnamon has emerged as a potential ally for women with PCOS. Shown to positively affect insulin resistance, cinnamon is regarded for its ability to regulate menstruation. Its anti-inflammatory properties make it a valuable addition to dietary strategies aimed at managing PCOS symptoms.

Dosage: 500 mg to 2 grams per day.

Mechanism: Cinnamon has shown positive effects on insulin resistance and may help regulate menstruation in women with PCOS.

Best Time to Take: It can be taken with meals, such as sprinkled on oatmeal or added to a smoothie.


Turmeric, a vibrant spice containing the active compound curcumin, has garnered attention for its potential to decrease insulin resistance and act as an anti-inflammatory agent. With roots in traditional medicine, turmeric holds promise for women with PCOS seeking a natural approach to addressing hormonal imbalances.

Dosage: 500-2,000 mg per day of curcumin (active ingredient in turmeric).

Mechanism: Curcumin in turmeric may decrease insulin resistance and act as an anti-inflammatory agent, potentially alleviating PCOS symptoms.

Best Time to Take: Ideally with meals to enhance absorption.


As a trace element, zinc plays a crucial role in boosting fertility and addressing unwanted hair growth and alopecia in women with PCOS. With its diverse benefits, zinc stands out as a valuable supplement for those aiming to optimize their reproductive health and manage associated symptoms.

Dosage: 15-30 mg per day.

Mechanism: Zinc, a trace element, can boost fertility and improve symptoms like unwanted hair growth and alopecia associated with PCOS.

Best Time to Take: Usually taken with a meal to enhance absorption, but it can be taken with or without food.

Evening Primrose Oil:

Derived from the evening primrose plant, this oil is known for its potential to alleviate period pain, regulate menstruation, and improve cholesterol levels in women with PCOS. Rich in essential fatty acids, evening primrose oil offers a holistic approach to managing various aspects of PCOS.

Dosage: 1,000-3,000 mg per day.

Mechanism: Evening primrose oil may help with period pain, and irregular menstruation, and improve cholesterol levels in women with PCOS.

Best Time to Take: Typically with meals to improve absorption.

Combined Vitamin D and Calcium:

Addressing the prevalent vitamin D deficiency in women with PCOS, the combination of vitamin D and calcium emerges as a cornerstone supplement. Beyond promoting bone health, this combination aids in improving irregular periods and enhancing ovulation, contributing to comprehensive PCOS management.

Dosage: Vitamin D: 1,000-4,000 IU; Calcium: 1,000-1,300 mg per day.

Mechanism: Essential for the endocrine system, this combination addresses common vitamin D deficiency in women with PCOS, improving irregular periods and promoting ovulation.

Best Time to Take: Vitamin D is often best taken in the morning, while calcium is recommended with meals.

Cod Liver Oil:

Harvested from the liver of codfish, cod liver oil is a nutrient-rich supplement offering vitamins D and A, along with omega-3 fatty acids. Renowned for its benefits in promoting menstrual regularity and aiding in weight management, cod liver oil provides essential support for women with PCOS.

Dosage: Follow product recommendations; usually 1-2 teaspoons per day.

Mechanism: Rich in vitamins D and A, omega-3 fatty acids in cod liver oil benefit menstrual regularity and weight management in women with PCOS.

Best Time to Take: With meals to enhance absorption.


Hailing from Chinese medicine, berberine stands out as an herbal supplement with potential benefits for insulin resistance. Widely used to enhance metabolism and balance endocrine responses, berberine offers a natural approach to managing key aspects of PCOS.

Dosage: 500-1,500 mg per day.

Mechanism: An herb in Chinese medicine, berberine may help with insulin resistance, potentially improving metabolism and balancing endocrine responses.

Best Time to Take: Typically with meals.

While supplements can complement PCOS management, it’s essential to consult with a healthcare professional before starting any regimen. Dosages may vary based on individual needs, and the best time to take supplements can depend on factors such as absorption rates and potential interactions. A personalized approach, in collaboration with a healthcare provider, ensures the most effective and safe use of supplements in addressing PCOS symptoms.

In embracing holistic approaches, women with PCOS can nurture their well-being and reclaim control over their health journey.

Disclaimer: The information provided herein is for educational purposes and general guidance only. Consult with a qualified healthcare professional before initiating any herbal or dietary supplement regimen, especially if pregnant, nursing, or undergoing medical treatment.

Reference :

  1. The effect of nutrient supplementation in the management of polycystic ovary syndrome-associated metabolic dysfunctions: A critical review – (

Source: Medindia

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