The trial took place over 18 months at UHN’s Toronto General Hospital, the Medical University of Vienna, and Hospital Universitario Puerta de Hierro-Majadahonda in Madrid. The ability to extend the lifespan of the donor organ poses several advantages.
Ultimately, these advantages will allow for more lungs to be utilized across farther geographies and the ability to improve recipient outcomes by converting Lung transplantation into a planned rather than urgent procedure.
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Some advantages of this new 10 degrees Celsius standard for lung storage include the potential to reduce or eliminate the 24/7 schedule and urgency of lung transplant procedures. By increasing the length of time the donors lungs are viable, transplant surgeries could become planned procedures, which avoids bumping scheduled surgeries and overnight transplantation.
This advancement in practice comes at a critical time when hospital resources are stretched and there are increased surgical backlogs due to the pandemic.
The study also suggests the new preservation temperature will allow more time to optimize immunologic matching between donor and recipients, and the possibility of performing lung transplantation in a semi-elective rather than urgent fashion.
Source: Eurekalert
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