Bromodomain Containing Protein 4 drugs in development by Therapy Areas, Indications, Stages, MoA, RoA, Molecule Type, and Key Players, 2023
The report also covers products from therapy areas such as Oncology, Respiratory, and Dermatology which include the indications Solid Tumor, Ovarian Cancer, Idiopathic Pulmonary Fibrosis, Dermatitis (Eczema), and Vitiligo. It also reviews key players involved in Bromodomain Containing Protein 4 targeted therapeutics development with respective active and dormant or discontinued products.
The Bromodomain Containing Protein 4 pipeline targets constitutes close to 54 molecules. Out of which, approximately 42 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 2, 10, 13, 2, 21, and 11 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 6, and 6 molecule.
Bromodomain Containing Protein 4 overview
Bromodomain-containing protein 4 is a protein encoded by the BRD4 gene. It plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. It promotes phosphorylation of Ser-2 of the C-terminal domain (CTD) of RNA polymerase II. It acts as a regulator of p53/TP53-mediated transcription.
For a complete picture of Bromodomain Containing Protein 4’s drug pipeline, buy the report here.
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