These methods allowed scientists to perform the largest and most comprehensive screen of cryoprotectant agents to determine their toxicity and efficiency at preserving complex organ systems during storage at -10°C. As a result,
“Zebrafish are a powerful model system that has never been used in the context of solid organ preservation for transplantation, despite several advantages,” said corresponding author Shannon N. Tessier, Ph.D., of the Center for Engineering in Medicine and Surgery, Harvard Medical School. “We hope this research will encourage others in transplantation sciences to leverage this important model organism.”
Reference :
- Zebrafish as a high throughput model for organ preservation and transplantation research – (https://onlinelibrary.wiley.com/doi/10.1096/fj.202300076R)
Source: Eurekalert
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