“From a clinical perspective and a public health perspective, we found some important take-home messages in this study,” Niculescu said. “High-risk patients should possibly be followed more closely the week of the full moon, during late afternoons and perhaps the month of September.”
What Causes the Increase in Suicide in People with Mental Health Disorders on the Full Moon?
Niculescu and his team previously developed blood biomarker tests for other mental health conditions (anxiety, depression, and post-traumatic stress disorder) and for pain. Using blood samples previously taken by the coroner from some of the people, the team was able to see which biomarkers were present.
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“We tested a list of top blood biomarkers for suicidality that we identified in previous studies,” Niculescu said. “The biomarkers for suicidality that are predictive of death by suicide during full moon, peak hour of day and peak month of the year compared to outside of those periods appear to be genes that regulate the body’s own internal clock, so called ‘circadian clock’. Using the biomarkers, we also found people with alcohol-use disorder or depression may be at higher risk during these time periods.”
Niculescu said the increased light from the full moon could be what leads to the increase in suicides during that period. Ambient light plays a major role on the body’s circadian rhythm, which is the natural 24-hour cycle our bodies follow to regulate when we are asleep and when we are awake. Moonlight could be impacting people at a time when it should be darker.
“The effect of ambient light and body clocks in suicide needs to be studied more closely, along with how people sleep and their exposure to light,” Niculescu said. “Changes in light can affect vulnerable people, in conjunction with other risk factors.”
As for the other two peak periods for suicides, Niculescu said the peak of suicides from 3 to 4 p.m. could be related to stressors throughout the day as well as a decrease in light beginning to occur that day, causing a lower expression of circadian clock genes and cortisol. And in September, many people are experiencing the end of summer vacations, which could cause stress, as well as seasonal affective disorder effects, as daylight decreases during that time of year.
In the future, Niculescu hopes to study if exposure to screens at night contributes to increased suicidality in people, especially younger people. “Some people have a full moon in their hand every night,” Niculescu said. “It’s an area we absolutely need to study further.”
Source: Eurekalert
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