Vasculitis drugs in development by stages, target, MoA, RoA, molecule type and key players, 2023

The report also covers the descriptive pharmacological action of the therapeutics and the latest news and press releases. Additionally, the report provides an overview of the key players involved in therapeutic development for Vasculitis and features dormant and discontinued products.

GlobalData tracks 30 drugs in development for Vasculitis by 29 companies/universities/institutes. The top development phase for Vasculitis is preclinical with 11 drugs in that stage. The Vasculitis pipeline has 29 drugs in development by companies and one by universities/ institutes. Some of the companies in the Vasculitis pipeline products market are: General Nanotherapeutics, Amgen and Johnson & Johnson.

The key targets in the Vasculitis pipeline products market include Interleukin 6 Receptor Subunit Alpha (IL6R1 or Membrane Glycoprotein 80 or CD126 or IL6R), Granulocyte Colony Stimulating Factor Receptor (CD114 or GCSFR or CSF3R), and Tyrosine Protein Kinase JAK1 (Janus Kinase 1 or JAK1 or EC 2.7.10.2).

The key mechanisms of action in the Vasculitis pipeline product include Tyrosine Protein Kinase JAK1 (Janus Kinase 1 or JAK1 or EC 2.7.10.2) Inhibitor with two drugs in Phase III. The Vasculitis pipeline products include seven routes of administration with the top ROA being Intravenous and nine key molecule types in the Vasculitis pipeline products market including Small Molecule, and Monoclonal Antibody.

Vasculitis overview

Vasculitis is a term that refers to a group of diseases that cause inflammation of the blood vessels, affecting both arteries and veins. Vasculitis can have various causes, such as genetic factors, infections, immune system disorders, blood cancers, or reactions to certain drugs. Vasculitis can affect different parts of the body, such as the skin, muscles, joints, nerves, lungs, heart, digestive system, kidneys, and eyes. Depending on the type and severity of vasculitis, the symptoms and complications may vary. Some common signs of vasculitis are fever, weight loss, fatigue, headache, joint pain, skin rash, and bleeding under the skin. Vasculitis can be diagnosed by blood tests, imaging tests, or biopsy of the affected tissue. Treatment options depend on the type and cause of vasculitis, but usually involve medications to reduce inflammation and prevent flare-ups.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s pipeline drugs offers detailed profiles of pharmaceutical drugs in all stages of pre-clinical and clinical development, from discovery through to pre-registration. Coverage is limited to novel human medicinal drugs and biosimilars seeking market approval proprietary and is one of two primary repositories of pharmaceutical drug information offered by GlobalData through its Pharmaceutical Intelligence Center.