Previous studies have suggested that this form of intermittent fasting may improve cardiometabolic health and blood sugar levels.
However, Bruno and colleagues wanted to determine whether these improvements are related to weight loss or the fasting strategy.
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They developed a randomized seven-day isocaloric crossover supervised feeding study comparing eTRF (80% of calories consumed before 1 p.m.) to a usual feeding pattern (50% of calories consumed after 4 p.m.) among 10 participants with prediabetes and obesity.
Empowering Glucose Stability
The patients were randomized 1:1 to eTRF or usual feeding patterns for days 1-7 and were changed over to the alternate arm on days 8-14.
Food was provided to meet the patients’ caloric needs for weight maintenance to determine the weight-independent effects of this strategy. The researchers performed glucose tolerance tests at baseline, crossover (day 7), and at the end of the study (day 14).
The researchers discovered that the participants weights were stable throughout the study. They found eTRF led to a decreased mean amplitude of glycemic excursion (MAGE) and decreased time above range, compared to the usual eating pattern group. The time in range was similar between the eTRF and the usual feeding pattern group.
“Eating the majority of one’s calories earlier in the day reduces the time that the blood sugar is elevated, thereby improving metabolic health,” Bruno said.
These findings suggest that eTRF has the potential to improve blood glucose levels, independent of weight. However, more studies are needed to understand the true benefit of these intervention strategies, the researchers said.
Source: Eurekalert
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