Pharma News

Shorla acquires methotrexate solution from Therakind in the US 


Shorla Oncology has acquired the oncology and autoimmune drug Jylamvo (methotrexate) from Therakind, for commercialisation in the US market. 

Jylamvo was approved by the US Food and Drug Administration (FDA) approval in November 2022, to treat adults with acute lymphoblastic leukaemia, mycosis fungoides, relapsed or refractory non-Hodgkin lymphoma, rheumatoid arthritis and severe psoriasis.  

Shorla is headquartered in Ireland and has operations in the US. The company had raised $35m earlier this month to advance its oncology pipeline.  

Jylamvo is an oral solution, making the treatment accessible to patients who may struggle taking tablets or other dosage forms. Commercialisation is set to begin immediately in the US. 

Chief Technical Officer and founder of Shorla Oncology Orlaith Ryan said: “This acquisition will provide a much-needed treatment to patients in need. It brings a crucial oral treatment to a larger patient population who suffer from cancer and other debilitating illnesses.” 

In March, Shorla Oncology received FDA approval for the nelarabine injection, an oncology drug, to treat T-cell leukaemia, an aggressive blood and bone marrow cancer that progresses quickly. The oncology drug has been approved to treat T-cell lmphoblastic lymphoma (T-LBL) and T-cell acute lymphoblastic leukemia (T-ALL). 

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A few months prior, the company had also signed a licensing agreement and strategic collaboration with an undisclosed drug development and a production firm in the UK to commercialise a chemotherapy drug, PIP-101, in the US.   




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