Intermittent fasting diets have become popular in recent years as an effective weight loss method. With intermittent fasting, you only eat during a specific window of time. Fasting for a certain number of hours each day or eating just one meal a couple of days a week can help your body burn fat. Research shows intermittent fasting can lower your risk of diabetes and heart disease.
“Type 2 diabetes is not necessarily a permanent, lifelong disease. Diabetes remission is possible if patients lose weight by changing their diet and exercise habits,” said Dongbo Liu, Ph.D., of Hunan Agricultural University in Changsha, China. “Our research shows an intermittent fast, Chinese Medical Nutrition Therapy (CMNT), can lead to diabetes remission in people with type 2 diabetes, and these findings could have a major impact on the over 537 million adults worldwide who suffer from the disease.”
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The researchers conducted a 3-month intermittent fasting diet intervention among 36 people with diabetes and found almost 90% of participants, including those who took blood sugar-lowering agents and insulin, reduced their diabetes medication intake after intermittent fasting. Fifty-five percent of these people experienced diabetes remission, discontinued their diabetes medication, and maintained it for at least one year.
The study calls into question the widely held belief that diabetes remission can only be achieved in people who have had the disease for a short period (0-6 years). Sixty-five percent of the study participants who achieved diabetes remission had a diabetes duration of more than 6 years (6-11 years).
“Diabetes medications are costly and a barrier for many patients who are trying to effectively manage their diabetes. Our study saw medication costs decrease by 77% in people with diabetes after intermittent fasting,” Liu said.
Therapeutic fasting has been shown in case studies and randomized trials to overcome insulin resistance, resulting in the discontinuation of insulin medication while maintaining blood sugar levels. IF is effective in glycemic control and other metabolic parameters, such as reducing visceral fat and controlling inflammatory mediators and markers such as C-reactive protein (CRP) and interleukin-6 (IL-6), but control of obesity is its most significant effect because it is a risk factor for T2DM. Several case studies have revealed a decrease in increased hemoglobin A1c (HbA1c) levels in people following fasting, which some attribute to sirtuin-6 (SIRT6) proteins. SIRT6 proteins are thought to be responsible for blood glucose homeostasis and the reversal of insulin resistance by boosting its sensitivity (2✔ ✔Trusted Source
Intermittent Fasting: A User-Friendly Method for Type 2 Diabetes Mellitus
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Because this protein family is enhanced after fasting, researchers will be able to better understand its mechanism of action and potential therapeutic implications on T2DM. With an alarming rise in the global incidence of T2DM, a cost-effective method to treat the disease with easy patient compliance is necessary, and intermittent fasting may be the solution.
References :
- Time-restricted Eating for the Prevention and Management of Metabolic Diseases – (https://pubmed.ncbi.nlm.nih.gov/34550357/)
- Intermittent Fasting: A User-Friendly Method for Type 2 Diabetes Mellitus – (https://www.cureus.com/articles/68373-intermittent-fasting-a-user-friendly-method-for-type-2-diabetes-mellitus)
Source: Medindia
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