Patent Filed by Ferring International Center SA for Treating Inflammatory Bowel Disease with Bacteriophages
According to GlobalData’s company profile on Ferring International Center, was a key innovation area identified from patents. Ferring International Center‘s grant share as of February 2024 was 50%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US11918613B2) discloses a pharmaceutical composition comprising bacteriophages capable of inducing a lytic infection in an adherent-invasive Escherichia coli strain. The composition includes specific bacteriophages of strains P2, P8, and CLB P2, deposited with the French National Collection of Microorganisms at the Institut Pasteur, along with a pharmaceutically acceptable carrier containing various auxiliary agents. The bacteriophages in the composition are lyophilized and can be administered through various routes such as oral, rectal, nasal, or topical, with specific dosage forms like pills, tablets, suppositories, or enemas.
Furthermore, the patent claims encompass different formulations and dosages of the composition, ranging from oral administration in various forms to rectal administration in suppositories or enemas. The dosage forms contain specific quantities of bacteriophages per dose, ensuring efficacy in targeting the adherent-invasive Escherichia coli strain. Additionally, the composition may include other bacteriophages from strains P1, P3, P4, P5, and P6, deposited with the French National Collection of Microorganisms at the Institut Pasteur, to enhance its lytic activity and sequence identity. This patent highlights the potential of bacteriophages as a targeted therapeutic approach against specific bacterial strains, offering a novel pharmaceutical composition for combating infections caused by adherent-invasive Escherichjson E. coli.
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