Of the 9 who had HIV, 6 were receiving antiretroviral therapy. All patients had classic mpox lesions, most often on the trunk (81.8 percent), anogenital area (72.7 percent), arms or legs (72.7 percent), face (72.7 percent), and palms and soles (45.4 percent).The most common systemic symptoms were fever (72.7 percent), muscle pain (72.7 percent), weakness (63.6 percent), swollen lymph nodes (63.6 percent), and headache (45.4 percent).
The most common findings in the 11 patients with ocular conditions were follicular conjunctivitis also known as pink eye (6 patients), eyelid lesions (6), episcleritis (inflammation of the clear tissue layer covering the white parts of the eye; 1), and keratitis (inflammation of the cornea; 1). The eye conditions resolved within one month in all but the keratitis patient, who improved after treatment with topical interferon alfa-2b (the antiviral drugs recommended for severe mpox aren’t available in Mexico).
The researchers noted that the 11 percent rate of ocular manifestations is higher than those reported in previous studies, probably because they included an ocular assessment in the initial physical exam, and an ophthalmologic exam was performed for all patients with moderate to severe skin lesions.While most patients with ocular manifestations had HIV, the patient with keratitis did not, “which could reflect that severe ocular involvement is not exclusive to people with immunosuppression,” the researchers said in the paper. “There may be cases with severe ocular affection and with a permanent vision impairment, even in immunocompetent people,” they said.
Reference :
- Spectrum of ophthalmic manifestations in monkeypox virus infection worldwide – (https://www.sciencedirect.com/science/article/pii/S2405844023057699)
Source: IANS
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