“However, one thing has remained the same, the need for the evaluation of three markers. These three markers; the expression of estrogen, progesterone, and HER2, are all molecular targets for treatment regimens, and are relied on by clinicians.”
Triple-negative breast cancer is a type of breast cancer that is ER negative, PR negative and lacks over expression of HER2. The cancer accounts for 10 to 20% of invasive breast cancers and has a poor prognosis or outcome. ER stands for estrogen receptors. Breast cancer cells that have estrogen receptors are sensitive to estrogen, the female hormone, which promotes the growth of the cancer.
“Chemotherapy is the staple treatment for TNBC patients. However, they lack the expression of three key therapeutic markers. The lack of therapeutic markers leads to poorer outcomes in TNBC.”
Source: Newswise
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