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Woman of the Week: Denali Therapeutics’ Cindy Dunkle

Welcome to the Woman of the Week podcast, a weekly discussion that illuminates the unique stories of women leaders who are catalyzing change throughout the life sciences industry. You can check out all our podcast episodes here.

“Your comfort zone is your failure zone.” This sage advice, made even more impressive coming from a teenager, gave Cindy Dunkle the courage to make a daring career leap.

“At that time, my daughter was in ninth grade and she said ‘I need a positive role model to show me how to do hard things.’ I think back on so many different points in time where I may have forfeited an opportunity because I was comfortable,” Dunkle said. “And it left a lasting impression. I’m so grateful for that wise insight … that I now test myself and always question my level of comfort. We have to stretch. We have to get crazy. We have to do the hard stuff.”

Dunkle joined Denali Therapeutics as chief people officer almost eight years ago after nearly a decade in HR roles at Genentech. From the start, she has been focused on supporting the people, culture and talent of “Denalians” who are doing the hard work of trying to solve the challenges associated with neurodegenerative diseases such as Alzheimer’s, Parkinson’s and ALS.

“There’s an unfortunate graveyard of failure out there,” she said. “Fortunately, we’re making progress. We have assembled a group of individuals who are committed to defeating degeneration. They’re unstoppable. They’re passionate. And I feel strongly, people need to be our focus to help them carry out our objectives.”

Dunkle said her role around “human capital management” and developing a culture that encourages innovation is continually evolving and needs to keep pace with the world. Recently, she and her team devised a “culture” equation that takes into account the inputs that add, multiply or subtract from employees feeling engaged, such as opportunity, connections and growth. At the same time, they also looked at what subtracts from a culture, like uncertainty and skill gaps.

“Very early on, we realized that people are the key drivers of our culture,” she said. “We placed a significant value on the uniqueness and the individuality of every Denalian, and we asked them to share their personal connection to our purpose and their past experience through a tagline that represents their own lived experience. For example, at one point in time, our CEO’s mother, who suffered from Alzheimer’s, said something to the effect, ‘Can you use your brain to fix my brain?’ And his tagline is: using our brains to fix your brains. There’s an intimacy and something very purposeful and connected around the intention of why he does what he does and how he leads. It’s personal. When we understand this about each person, we have a way of being able to connect and support and to sustain one another in doing hard things.”

 

In this episode of the Woman of the Week podcast, Dunkle shares her vision for creating a people-first culture, how investing in STEM can lead to future success and why DEI is not an option but an obligation.

Welcome to WoW, the Woman of the Week podcast by PharmaVoice powered by Industry Dive. In this episode, Taren Grom, editor-in-chief emeritus at PharmaVoice meets with Cindy Dunkle, chief people officer of Denali Therapeutics.

Taren: Cindy, welcome to the WoW podcast program.

Cindy: Great to be with you.

Taren: So grateful to have you with us. Cindy, you have almost 30 years of experience in compensation, organizational design, and talent acquisition. I’ve been noting that many companies are phasing out the term human resources to be more people-focused which really ties to your title. Can you talk us through this evolution in general and what your role means specifically in your organization?

Cindy: I’m so glad you asked this because there is a dynamic of our resources to humans. And with that traditionally, human resources have – it’s been focused on policies and practices and operations with a heavy hand in things like compliance and government relations. What I have seen over time and specifically as I relate to the work that I do with Denali, a chief people officer in most cases is still responsible for these practice areas but a primary emphasis is placed on the focus of people, culture, nurturing talent, recognizing the importance of human capital. And over the time with Denali, for me, it’s just simply about loving people, genuinely caring about their desire to have an impact while understanding their personal circumstance, connecting with them, relating and working together.

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