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How pharma’s rocky real estate market has changed — for better and worse

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As investments poured into the biotech sector during the COVID-19 pandemic, companies flooded the real estate market looking for space to develop the next big drugs, which ratcheted up demand and triggered a surge in life sciences focused construction.

But as capital markets have dried up — forcing many in the industry to rethink growth plans — and interest rates have soared, building developers and biotechs alike have begun pumping the brakes.

“There was a frenzy of trying to find bio space to a point where it was hard to keep up with what was happening,” Kathy Gigac, a principal and managing director at Avison Young said. “That has definitely slowed and people are being a little bit more thoughtful about it (now).”

A slew of construction projects that commenced during the pandemic hey-days are expected to hit the market in the coming months, but what will come after is more uncertain.

“Everything that’s underway and the stuff going into permitting right now — that’s moving forward. But (what’s) maybe a little bit more tentative is starting new projects and opportunities,” Zachary Richards, a senior project manager at the land development consulting firm Bohler said, noting that many builders are beginning to rethink their strategy for life sciences projects.

Professional headshot of Zachary Richards

Zachary Richards, senior project manager, Bohler

Permission granted by Bohler

 

A recent report published by CBRE found that lab space inventory increased by nearly 50% over the last five years, and lab vacancy rates rose across the top 13 U.S. life sciences hubs in the first quarter of 2023, with availability in some areas up fivefold from just a year ago. And last month, Alexandria Real Estate Equities, one of the largest biotech property groups, announced it was postponing some projects and reducing its construction spending this year due to increasing costs and persistent supply chain delays.

“(The) thought is — let’s spend most of 2023 getting things permitted, get ready to go in for a building permit maybe at the end of the year, and start building in the spring,” Richards said. “By then maybe interest rates (will) have righted and it won’t be as bad trying to find financing to get these things constructed.”

Despite the turmoil, many major pharma and biotech players are still looking to expand their lab space. Here are the major trends they’ll need to navigate in the real estate market.

A power shift

With the deluge of new construction and cooling demand, life sciences tenants now have more room to negotiate with landlords and developers who want to fill their spaces. The power dynamics have completely changed, Matthew Powers, CEO of Nan Fung Life Sciences Real Estate, said.

“The companies that are continuing to grow and looking for additional real estate in this market are the high-quality companies that are passing the high level of scrutiny from private investors,” he contended. “There’s a flight to quality, and so they’re demanding more of their landlords.”

Professional headshot of Matthew Powers

Matthew Powers, CEO, Nan Fun Life Sciences Real Estate 

Permission granted by Matthew Powers 

 

Rather than choosing landlords and developers with properties across sectors, he suggested that more drugmakers now look for partners who can “be an extension of their organization and have an intimate understanding of their science,” which can go a long way toward ensuring that an office and lab space is outfitted with all the tools needed for the company’s specific technology or indication area.

Gigac echoed the same sentiment, adding that “it comes down to making sure you have the right partner with you to guide you through the process properly.”

However, because of the COVID-19 demand surge, more developers have entered the life sciences facilities space, making the process of choosing a partner more arduous for biotechs.

“I think tenants should put a lot of time and energy into essentially a (know your customer) process. Right now, know who your developer is. Highly scrutinize them, then find out how much leverage is on a project,” Powers advised. “Because you don’t want to be six months into a process and thinking you’re going to hire people to advance your science platform and then find out the landlord can’t finish the project or doesn’t have the funds or is going to try and pass through increased interest rates to you.”

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